Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment

• Main Authors: Monika Chomczyk (Author), Luca Gazzola (Author), Shubhankar Dash (Author), Patryk Firmanty (Author), Binsah S. George (Author), Vakul Mohanty (Author), Hussein A. Abbas (Author), Natalia Baran (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute myeloid leukemia (AML), an aggressive malignancy of hematopoietic stem cells, is characterized by the blockade of cell differentiation, uncontrolled proliferation, and cell expansion that impairs healthy hematopoiesis and results in pancytopenia and susceptibility to infections. Several geneti...