Population Pharmacokinetics and Dose Optimization of Ceftazidime and Imipenem in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

• Main Authors: Thu-Minh Nguyen (Author), Thu-Hue Ngo (Author), Anh-Quan Truong (Author), Dinh-Hoa Vu (Author), Dinh-Chi Le (Author), Ngan-Binh Vu (Author), Tuyet-Nga Can (Author), Hoang-Anh Nguyen (Author), Thu-Phuong Phan (Author), Françoise Van Bambeke (Author), Céline Vidaillac (Author), Quy-Chau Ngo (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Ceftazidime and imipenem have been increasingly used to treat Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) due to their extended-spectrum covering <i>Pseudomonas aeruginosa</i>. This study aims to describe the population pharmacokinetic (PK) and pharm...