Toxicity evaluation of methoxy poly(ethylene oxide)-block-poly(ε-caprolactone) polymeric micelles following multiple oral and intraperitoneal administration to rats

• Autori principali: Ziyad Binkhathlan (Autore), Wajhul Qamar (Autore), Raisuddin Ali (Autore), Hala Kfoury (Autore), Mohammed Alghonaim (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2017-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Methoxy poly(ethylene oxide)-block-poly(ɛ-caprolactone) (PEO-b-PCL) copolymers are amphiphilic and biodegradable copolymers designed to deliver a variety of drugs and diagnostic agents. The aim of this study was to synthesize PEO-b-PCL block copolymers and assess the toxic effects of drug-free PEO-b...