Inhibition survey with phenolic compounds against the δ- and η-class carbonic anhydrases from the marine diatom thalassiosira weissflogii and protozoan Plasmodium falciparum

• Principais autores: Siham A. Alissa (Autor), Hanan A. Alghulikah (Autor), Zeid A. ALOthman (Autor), Sameh M. Osman (Autor), Sonia Del Prete (Autor), Clemente Capasso (Autor), Alessio Nocentini (Autor), Claudiu T. Supuran (Autor)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The inhibition of δ- and η-class carbonic anhydrases (CAs; EC 4.2.1.1) was poorly investigated so far. Only one δ-CA, TweCA from the diatom Thalassiosira weissflogii, and one η-CA, PfCA, from Plasmodium falciparum, have been cloned and characterised to date. To enrich δ- and η-CAs inhibition profile...