Indirect Comparison of Combined BRAF and MEK Inhibition in Melanoma Patients with Elevated Baseline Lactate Dehydrogenase

• Main Authors: Valerie Glutsch (Author), Teresa Amaral (Author), Claus Garbe (Author), Kai-Martin Thoms (Author), Peter Mohr (Author), Axel Hauschild (Author), Bastian Schilling (Author)
• Format: Book
• Published: Medical Journals Sweden, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The approval of BRAF and MEK inhibitors has significantly improved treatment outcomes for patients with BRAF-mutated metastatic melanoma. The 3 first-line targeted therapy trials have provided similar results, and thus the identification of predictive biomarkers may generate a more precise basis for...