Modeling gene-environment interactions in longitudinal family studies: a comparison of methods and their application to the association between the IGF pathway and childhood obesity

• Auteurs principaux: Cheng Wang (Auteur), Marie-Hélè (Auteur), Jean-François Lefebvre (Auteur), Kelly M. Burkett (Auteur), Lise Dubois (Auteur)
• Format: Livre
• Publié: BMC, 2019-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background The interactive effect of the IGF pathway genes with the environment may contribute to childhood obesity. Such gene-environment interactions can take on complex forms. Detecting those relationships using longitudinal family studies requires simultaneously accounting for correlati...