[Final accepted version, unedited] Exploring the inhibitory mechanisms of indazole compounds against SAH/MTAN-mediated quorum sensing utilizing QSAR and docking

• Autori principali: Sisir Nandi (Autore), Mohit Kumar (Autore), Rashmi Kumari (Autore), Aaruni Saxena (Autore)
• Natura: Libro
• Pubblicazione: AboutScience Srl, 2022-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The world is under the great threat of antimicrobial resistance (AMR) leading to premature deaths. Micro-organisms can produce AMR via quorum sensing mechanisms utilizing S-adenocylhomocystiene/methiothioadenosine nucleosidase (SAH/MTAN) biosynthesis. But there is no specific drug developed till dat...