Multivariate transcriptome analysis identifies networks and key drivers of chronic lymphocytic leukemia relapse risk and patient survival

• Autores principales: Ti'ara L. Griffen (Autor), Eric B. Dammer (Autor), Courtney D. Dill (Autor), Kaylin M. Carey (Autor), Corey D. Young (Autor), Sha'Kayla K. Nunez (Autor), Adaugo Q. Ohandjo (Autor), Steven M. Kornblau (Autor), James W. Lillard (Autor)
• Formato: Libro
• Publicado: BMC, 2021-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Chronic lymphocytic leukemia (CLL) is an indolent heme malignancy characterized by the accumulation of CD5+ CD19+ B cells and episodes of relapse. The biological signaling that influence episodes of relapse in CLL are not fully described. Here, we identify gene networks associate...