Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice
Abstract Background Apremilast, an oral phosphodiesterase (PDE) 4 inhibitor, has demonstrated efficacy in psoriasis, while its efficacy in atopic dermatitis (AD) was found to be modest. AD is a chronic inflammatory skin disease associated with activation of T helper (Th) 2 and Th17 immunity and a co...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Adis, Springer Healthcare,
2019-10-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |