Preclinical studies of NOS inhibitor T1059 vasopressor activity on the models of acute hemorrhagic shock in rats and dogs

• Main Authors: Marina Filimonova (Author), Ljudmila Shevchenko (Author), Victoria Makarchuk (Author), Alina Saburova (Author), Petr Shegay (Author), Andrey Kaprin (Author), Sergey Ivanov (Author), Alexander Filimonov (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of new effective and safe vasopressors is one of the ways to increase the effectiveness of the treatment of hypotensive disorders, the severe forms of which remain a common cause of death in all countries of the world. Previously, we synthesized the original compound T1059, a selecti...