Role of molecular adsorbent recirculating system in methotrexate-induced acute liver failure: a case report and literature review

• Главные авторы: T. Corbisier (Автор), André O. Von Bueren (Автор), W.B. Breunis (Автор), S. Grazioli (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Предметы: article
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We describe the case of a 14-year-old girl with osteosarcoma who was treated with high-dose methotrexate (12 g/m2). Twenty-four hours after the infusion, her plasma methotrexate concentration was elevated at 937 μmol/L (normal < 10 µmol/L). She exhibited severe signs of methotrexate toxicity, inc...