Role of molecular adsorbent recirculating system in methotrexate-induced acute liver failure: a case report and literature review
We describe the case of a 14-year-old girl with osteosarcoma who was treated with high-dose methotrexate (12 g/m2). Twenty-four hours after the infusion, her plasma methotrexate concentration was elevated at 937 μmol/L (normal < 10 µmol/L). She exhibited severe signs of methotrexate toxicity, inc...
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Frontiers Media S.A.,
2024-08-01T00:00:00Z.
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