De novo chronic lymphocytic leukemia/prolymphocytic leukemia or B-cell prolymphocytic leukemia? The importance of integrating clinico-morphological and immunophenotypic findings in distinguishing chronic lymphoproliferative diseases with circulating phase

• Main Authors: Zachariah Chowdhury (Author), Yookarin Khonglah (Author), Susmita Sarma (Author), Pranjal Kalita (Author)
• Format: Book
• Published: University of São Paulo, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

B-cell prolymphocytic leukemia (B-PLL) is an extremely rare disease, accounting for approximately 1% of the lymphocytic leukemias. B-PLL generally occurs in older people. It is characterized by the presence of more than 55% prolymphocytes in the peripheral blood (PB), no or minimal lymphadenopathy,...