Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series

• Main Authors: James McDonald (Author), Judith Sayers (Author), Stefan D. Anker (Author), Jann Arends (Author), Trude Rakel Balstad (Author), Vickie Baracos (Author), Leo Brown (Author), Asta Bye (Author), Olav Dajani (Author), Ross Dolan (Author), Marie T. Fallon (Author), Eilidh Fraser (Author), Christine Griel (Author), Aleksandra Grzyb (Author), Marianne Hjermstad (Author), Mariam Jamal‐Hanjani (Author), Gunnhild Jakobsen (Author), Stein Kaasa (Author), Donald McMillan (Author), Matthew Maddocks (Author), Iain Philips (Author), Inger O. Ottestad (Author), Kieran F. Reid (Author), Mariana S. Sousa (Author), Melanie R. Simpson (Author), Ola Magne Vagnildhaug (Author), Richard J. E. Skipworth (Author), Tora S. Solheim (Author), Barry J. A. Laird (Author), the Cancer Cachexia Endpoints Working Group (Author)
• Format: Book
• Published: Wiley, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, it is not clear which physical function endpoints should be used....