A Dynamic Quantitative Systems Pharmacology Model of Inflammatory Bowel Disease: Part 2 - Application to Current Therapies in Crohn's Disease

• Váldodahkkit: Katharine V. Rogers (Dahkki), Steven W. Martin (Dahkki), Indranil Bhattacharya (Dahkki), Ravi Shankar Prasad Singh (Dahkki), Satyaprakash Nayak (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2021-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Inflammatory bowel disease (IBD) is a heterogeneic disease with a variety of treatments targeting different mechanisms. A multistate, mechanistic, mathematical model of IBD was developed in part 1 of this two‐part article series. In this paper, application of the model to predict response of key cli...