Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue

Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue

Objective: Studies in mice have shown that the decrease in lipoprotein lipase (LPL) activity in adipose tissue upon fasting is mediated by induction of the inhibitor ANGPTL4. Here, we aimed to validate this concept in humans by determining the effect of a prolonged fast on ANGPTL4 and LPL gene and p...

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Main Authors: Philip M.M. Ruppert (Author), Charlotte C.J.R. Michielsen (Author), Eric J. Hazebroek (Author), Ali Pirayesh (Author), Gunilla Olivecrona (Author), Lydia A. Afman (Author), Sander Kersten (Author)
Format: Book
Published: Elsevier, 2020-10-01T00:00:00Z.
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3rd Floor Main Library

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