Anti-EpCAM functionalized graphene oxide vector for tumor targeted siRNA delivery and cancer therapy

• Main Authors: Si Chen (Author), Shuang Zhang (Author), Yifan Wang (Author), Xin Yang (Author), Hong Yang (Author), Chunying Cui (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Graphene oxide (GO) has emerged as a potential drug delivery vector. For siRNA delivery, GO should be modified to endow it with gene delivery ability and targeting effect. However, the cationic materials used previously usually had greater toxicity. In this study, GO was modified with a non-toxicity...