Complement Inhibition in Severe COVID-19 Acute Respiratory Distress Syndrome

• Main Authors: Sharmila Raghunandan (Author), Cassandra D. Josephson (Author), Hans Verkerke (Author), W. Matthew Linam (Author), Treva C. Ingram (Author), Patricia E. Zerra (Author), Connie M. Arthur (Author), Sean R. Stowell (Author), Michael Briones (Author), Satheesh Chonat (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most children with COVID-19 have asymptomatic or mild illness. Those who become critically ill suffer from acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI). The rapid deterioration of lung function has been linked to microangiopathic and immune-mediated processes seen in the...