PGC-1α Is a Master Regulator of Mitochondrial Lifecycle and ROS Stress Response

• Main Authors: Othman Abu Shelbayeh (Author), Tasnim Arroum (Author), Silke Morris (Author), Karin B. Busch (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Mitochondria play a major role in ROS production and defense during their life cycle. The transcriptional activator PGC-1α is a key player in the homeostasis of energy metabolism and is therefore closely linked to mitochondrial function. PGC-1α responds to environmental and intracellular conditions...