The effect of celecoxib on orthodontic tooth movement and root resorption in rat.

• Main Authors: Ahmad Sodagar (Author), Tahura Etezadi (Author), Pouria Motahhary (Author), Ahmad Reza Dehpour (Author), Hamed Vaziri (Author), Arash Khojasteh (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhibition of prostaglandin (PGs) production leads to decrease in orthodontic tooth movement (OTM). It is not known whether inhibition of cyclooxygenase-1 (COX-1) or cyclooxygenase-2 (COX-2) is the key mechanism for this effect. In this study, the effect of celecoxib, a highly-selective COX-2 inhibi...