Role of beta-arrestin 2 downstream of dopamine receptors in the basal ganglia

• প্রধান লেখক: Thomas eDel'Guidice (লেখক), Morgane eLemasson (লেখক), Jean-Martin eBeaulieu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2011-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Multifunctional scaffolding protein beta-arrestins (βArr) and the G protein receptor kinases (GRK) are involved in the desensitization of several G protein coupled-receptors (GPCR). However, arrestins can also contribute to GPCR signaling independently from G proteins. In this review, we focus on th...