Harnessing Potential of ω-3 Polyunsaturated Fatty Acid with Nanotechnology for Enhanced Breast Cancer Therapy: A Comprehensive Investigation into ALA-Based Liposomal PTX Delivery

• Main Authors: Rohit Kumar (Author), Anurag Kumar (Author), Dharmendra Kumar (Author), Sneha Yadav (Author), Neeraj Kumar Shrivastava (Author), Jyoti Singh (Author), Archana Bharti Sonkar (Author), Pratibha Verma (Author), Dilip Kumar Arya (Author), Gaurav Kaithwas (Author), Ashish Kumar Agrarwal (Author), Sanjay Singh (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our hypothesis posited that incorporating alpha-linolenic acid (ALA) into liposomes containing Paclitaxel (PTX) could augment cellular uptake, decrease the therapeutic dosage, and alleviate PTX-related side effects. Our investigation encompassed characterization of the liposomal formulation, encompa...