Insufficient Stability of Clavulanic Acid in Widely Used Child-Appropriate Formulations

• Main Authors: Ines Mack (Author), Mike Sharland (Author), Janneke M. Brussee (Author), Sophia Rehm (Author), Katharina Rentsch (Author), Julia Bielicki (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amoxicillin-clavulanic acid (AMC) belongs to the WHO Essential Medicines List for children, but for optimal antimicrobial effectiveness, reconstituted dry powder suspensions need to be stored in a refrigerated environment. Many patients in low- and middle-income countries who are sold AMC suspension...