Comparative genomics and full-length Tprk profiling of Treponema pallidum subsp. pallidum reinfection.

• Principais autores: Amin Addetia (Autor), Lauren C Tantalo (Autor), Michelle J Lin (Autor), Hong Xie (Autor), Meei-Li Huang (Autor), Christina M Marra (Autor), Alexander L Greninger (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2020-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Developing a vaccine against Treponema pallidum subspecies pallidum, the causative agent of syphilis, remains a public health priority. Syphilis vaccine design efforts have been complicated by lack of an in vitro T. pallidum culture system, prolific antigenic variation in outer membrane protein TprK...