Comparative genomics and full-length Tprk profiling of Treponema pallidum subsp. pallidum reinfection.

• Main Authors: Amin Addetia (Author), Lauren C Tantalo (Author), Michelle J Lin (Author), Hong Xie (Author), Meei-Li Huang (Author), Christina M Marra (Author), Alexander L Greninger (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Developing a vaccine against Treponema pallidum subspecies pallidum, the causative agent of syphilis, remains a public health priority. Syphilis vaccine design efforts have been complicated by lack of an in vitro T. pallidum culture system, prolific antigenic variation in outer membrane protein TprK...