Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1

• Main Authors: Seung Hyeon Kim (Author), Su-Jung Kim (Author), Jeongmin Park (Author), Yeonsoo Joe (Author), So Eui Lee (Author), Soma Saeidi (Author), Xiancai Zhong (Author), Seong Hoon Kim (Author), Sin-Aye Park (Author), Hye-Kyung Na (Author), Hun Taeg Chung (Author), Young-Joon Surh (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor-associated macrophages (TAMs) represent one of the most abundant components of the tumor microenvironment and play important roles in tumor development and progression. TAMs display plasticity and functional heterogeneity as reflected by distinct phenotypic subsets. TAMs with an M1 phenotype h...