Nephrotoxicity of Calcineurin Inhibitors in Kidney Epithelial Cells is Independent of NFAT Signaling

Background: Calcineurin inhibitors (CNIs) such as cyclosporine A and tacrolimus are commonly used after renal transplantation to suppress the immune system. In lymphoid cells, cyclosporine A acts via the calcineurin/nuclear factor of activated T-cell (NFAT) axis. In non-lymphoid cells, such as kidne...

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Main Authors: Andrea Karolin (Author), Geneviève Escher (Author), Stefan Rudloff (Author), Daniel Sidler (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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