Leukocyte Telomere Length Variability as a Potential Biomarker in Patients with PolyQ Diseases

• Main Authors: Daniela Scarabino (Author), Liana Veneziano (Author), Alessia Fiore (Author), Suran Nethisinghe (Author), Elide Mantuano (Author), Hector Garcia-Moreno (Author), Gianmarco Bellucci (Author), Nita Solanky (Author), Maria Morello (Author), Ginevra Zanni (Author), Rosa Maria Corbo (Author), Paola Giunti (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SCA1, SCA2, and SCA3 are the most common forms of SCAs among the polyglutamine disorders, which include Huntington's Disease (HD). We investigated the relationship between leukocyte telomere length (LTL) and the phenotype of SCA1, SCA2, and SCA3, comparing them with HD. The results showed that...