Microsomal Prostaglandin E Synthase-1 Expression in Inflammatory Conditions Is Downregulated by Dexamethasone: Seminal Role of the Regulatory Phosphatase MKP-1

Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme situated downstream of cyclo-oxygenase-2, promoting the excessive PGE2 production in inflammation. Dexamethasone is known to suppress mPGES-1 but the mechanisms regulating mPGES-1 expression remain poorly known. MKP-1 is a phosph...

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Main Authors: Lauri Tuure (Author), Mari Hämäläinen (Author), Brendan J. Whittle (Author), Eeva Moilanen (Author)
Format: Book
Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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