The Role of Carbon Dioxide in the Rat Acute Stroke Penumbra

• Главные авторы: Leonard L. Yeo (Автор), Fabian Arnberg (Автор), Arvin Chireh (Автор), Vijay Sharma (Автор), Benjamin Tan (Автор), Vamsi Gontu (Автор), Philip Little (Автор), Staffan Holmin (Автор)
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• Опубликовано: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Предметы: article
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PurposeThe vasodilatory response to inhaled CO2 occurs in the acute stroke ischemic penumbra and may be a potential therapeutic modality.MethodsTwenty-two Sprague-Dawley rats were subjected to 90-min occlusion of the M2 segment of the middle cerebral artery (M2CAO) by endovascular technique. The ani...