The Role of Carbon Dioxide in the Rat Acute Stroke Penumbra

• Main Authors: Leonard L. Yeo (Author), Fabian Arnberg (Author), Arvin Chireh (Author), Vijay Sharma (Author), Benjamin Tan (Author), Vamsi Gontu (Author), Philip Little (Author), Staffan Holmin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeThe vasodilatory response to inhaled CO2 occurs in the acute stroke ischemic penumbra and may be a potential therapeutic modality.MethodsTwenty-two Sprague-Dawley rats were subjected to 90-min occlusion of the M2 segment of the middle cerebral artery (M2CAO) by endovascular technique. The ani...