Cardioprotective Effect of Grape Seed Extract on Chronic Doxorubicin-Induced Cardiac Toxicity in Wistar Rats

• Main Authors: Nasser Razmaraii (Author), Hossein Babaei (Author), Alireza Mohajjel Nayebi (Author), Gholamreza Assadnassab (Author), Javad Ashrafi Helan (Author), Yadollah Azarmi (Author)
• Formato: Libro
• Publicado: Tabriz University of Medical Sciences, 2016-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Purpose: The aim of the present study was to determine the ability of grape seed extract (GSE) as a powerful antioxidant in preventing adverse effect of doxorubicin (DOX) on heart function. Methods: Male rats were divided into three groups: control, DOX (2 mg/kg/48h, for 12 days) and GSE (100 mg/kg/...