A Novel STAT3 Mutation in a Qatari Patient With Hyper-IgE Syndrome

• Main Authors: Natalia S. Chaimowitz (Author), Justin Branch (Author), Anaid Reyes (Author), Alexander Vargas-Hernández (Author), Jordan S. Orange (Author), Lisa R. Forbes (Author), Mohammed Ehlayel (Author), Saleema C. Purayil (Author), Maryam Ali Al-Nesf (Author), Tiphanie P. Vogel (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autosomal dominant hyper-IgE syndrome caused by mutations in the transcription factor STAT3 (AD-HIES) is characterized by a collection of immunologic and non-immune features including eczema, recurrent infections, elevated IgE levels, and connective tissue anomalies. We report the case of a Qatari c...