MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1

Abstract Mesenchymal stem cell (MSC)-based therapy has emerged as a promising treatment for spinal cord injury (SCI), but improving the neurogenic potential of MSCs remains a challenge. Mixed lineage leukemia 1 (MLL1), an H3K4me3 methyltransferases, plays a critical role in regulating lineage-specif...

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Main Authors: Chen Zhang (Author), Weilong Ye (Author), Mengyao Zhao (Author), Lujue Long (Author), Dengsheng Xia (Author), Zhipeng Fan (Author)
Format: Book
Published: Nature Publishing Group, 2023-10-01T00:00:00Z.
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