Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation

• Автори: Xiaozhi Hu (Автор), Yanyang Nan (Автор), Yuting Zhang (Автор), Jiajun Fan (Автор), Hanqi Wang (Автор), Yu Bai (Автор), Yuanzhen Zhang (Автор), Xuyao Zhang (Автор), Zeguo Zhu (Автор), Zhonglian Cao (Автор), Xiaomiao Ye (Автор), Tao Wu (Автор), Shuwen Xu (Автор), Zhengyu Wu (Автор), Wei Hu (Автор), Dianwen Ju (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2024-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Atherosclerosis (AS) ultimately cause major adverse cardiovascular events (MACEs). While traditional strategies by lipid-reducing have reduced MACEs, many patients continue to face significant risks. It might attribute to the upregulation of CD47 expression in AS lesions, that mediated anti-efferocy...