Borneol and Α-asarone as adjuvant agents for improving blood-brain barrier permeability of puerarin and tetramethylpyrazine by activating adenosine receptors

• Autors principals: Jun-Yong Wu (Autor), Yong-Jiang Li (Autor), Le Yang (Autor), Yi-Yun Hu (Autor), Xiong-Bin Hu (Autor), Tian-Tian Tang (Autor), Jie-Min Wang (Autor), Xin-Yi Liu (Autor), Da-Xiong Xiang (Autor)
• Format: Llibre
• Publicat: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Puerarin (PUE) and tetramethylpyrazine (TMP) are central nervous system (CNS) drugs used in cerebrovascular diseases. Poor brain-blood barrier (BBB) permeability limited their clinical application. Borneol and α-asarone have been proposed as an oral brain-targeting enhancer. In this study, we aimed...