Computational drug design of potential α-amylase inhibitors using some commercially available flavonoids

• Main Authors: Arumugam Madeswaran (Author), Kuppusamy Asokkumar (Author), Muthuswamy Umamaheswari (Author), Thirumalaisamy Sivashanmugam (Author), Varadharajan Subhadradevi (Author), Puliyath Jagannath (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The primary objective of this study was to investigate the α-amylase inhibitory activity of flavonoids using in silico docking studies. In this perspective, flavonoids like biochanin, chrysin, hesperitin, morin, tricin and vitexycarpin were selected. Acarbose, a known α-amylase inhibitor was used as...