Effect of Storage Humidity on Physical Stability of Spray-Dried Naproxen Amorphous Solid Dispersions with Polyvinylpyrrolidone: Two Fluid Nozzle vs. Three Fluid Nozzle

• Main Authors: Sonal V. Bhujbal (Author), Yongchao Su (Author), Vaibhav Pathak (Author), Dmitry Y. Zemlyanov (Author), Alex-Anthony Cavallaro (Author), Eric J. Munson (Author), Lynne S. Taylor (Author), Qi (Tony) (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In a spray drying operation, a two-fluid nozzle (2FN) with a single channel is commonly used for atomizing the feed solution. However, the less commonly used three-fluid nozzle (3FN) has two separate channels, which allow spray drying of materials in two incompatible solution systems. Although amorp...