Long-term treadmill exercise improves spatial memory of male appswe/ps1de9 mice by regulation of BDNF expression and microglia activation

• Main Authors: JY Xiong (Author), SC Li (Author), YX Sun (Author), XS Zhang (Author), ZZ Dong (Author), P. Zhong (Author), XR Sun (Author)
• Format: Bog
• Udgivet: Termedia Publishing House, 2015-11-01T00:00:00Z.
• Fag: article
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Increasing evidence suggests that physical activity could delay or attenuate the symptoms of Alzheimer's disease (AD). But the underlying mechanisms are still not fully understood. To investigate the effect of long-term treadmill exercise on the spatial memory of AD mice and the possible role o...