FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice
Objective: Forkhead box protein O1 (FOXO1) plays a key role in regulating hepatic glucose production, but investigations of FOXO1 inhibition as a potential therapeutic approach have been hampered by a lack of selective chemical inhibitors. By profiling structurally diverse FOXO1 inhibitors, the curr...
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Main Authors: | Yun-Kyoung Lee (Author), Bryan Diaz (Author), Marianne Deroose (Author), Samuel X. Lee (Author), Sandro Belvedere (Author), Domenico Accili (Author), Rudolph L. Leibel (Author), Hua V. Lin (Author) |
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Format: | Book |
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Elsevier,
2021-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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