Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) ¹⁸F-Radiopharmaceuticals

• Main Authors: Lexi Gower-Fry (Author), Travis Kronemann (Author), Andreas Dorian (Author), Yinglan Pu (Author), Carolin Jaworski (Author), Carmen Wängler (Author), Peter Bartenstein (Author), Leonie Beyer (Author), Simon Lindner (Author), Klaus Jurkschat (Author), Björn Wängler (Author), Justin J. Bailey (Author), Ralf Schirrmacher (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules, such as peptides, proteins and biologically relevant small molecules, has improved the generation of ¹⁸F-radiopharmaceuticals for medical imaging. The efficient isotopic exchange radiof...