Green Formulation of Spironolactone Loaded Chitosan-Coated Nano Lipid Carrier for Treatment of Acne Vulgaris: A Randomized Double-Blind Clinical Trial

• Main Authors: Majid Saeedi (Author), Katayoun Morteza-Semnani (Author), Jafar Akbari (Author), Zohreh Hajheydari (Author), Amin Goodarzi (Author), Seyyed Sohrab Rostamkalaei (Author), Seyyed Mohammad Hassan Hashemi (Author), Seyyed Mobin Rahimnia (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Spironolactone (SPN), which is classified as an anti-androgen, has demonstrated efficacy in treating acne. This study aimed to utilize ultrasonication to create a chitosan-coated nano lipid carrier (NLC) for enhancing the delivery of SPN to the skin and treating acne. Methods: Various hydro...