Targeted inhibition of mRNA translation initiation factors as a novel therapeutic strategy for mature B-cell neoplasms

• Κύριοι συγγραφείς: Joe Taylor (Συγγραφέας), Alison M Yeomans (Συγγραφέας), Graham Packham (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Open Exploration Publishing Inc., 2020-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Cancer development is frequently associated with dysregulation of mRNA translation to enhance both increased global protein synthesis and translation of specific mRNAs encoding oncoproteins. Thus, targeted inhibition of mRNA translation is viewed as a promising new approach for cancer therapy. In th...