Comparison of intranasal and intraperitoneal administration of Eugenia caryophyllata (clove) essential oil on spatial memory, anxiety-like behavior and locomotor activity in a pilocarpine-induced status epilepticus rat model

• Main Authors: Fatemeh Parvizi (Author), Soraya Mehrabi (Author), Ayeh Naghizadeh (Author), Mohammad Kamalinejad‬ (Author), Sepide Goudarzi (Author), ‬‬‬‬‬‬‬‬‬‬ Maryam Farahmandfar (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Epilepsy induces behavioral effects and histological changes in the hippocampus. Eugenol, the main component of clove essential oil, has modulatory effects on seizure. We aimed to investigate the effect of intraperitoneal (IP) and intranasal (IN) clove essential oil on cognitive...