Resistance to PARP-inhibitors in Cancer Therapy

• Asıl Yazarlar: Alicia eMontoni (Yazar), Mihaela eRobu (Yazar), Emilie ePouliot (Yazar), Girish M. Shah (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2013-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The pharmacological inhibitors of poly(ADP-ribose) polymerase (PARP) family of proteins have shown promising results in preclinical studies and clinical trials as a monotherapy or in combination therapy for some cancers. Thus, usage of PARP-inhibitors (PARPi) in cancer therapy is bound to increase w...