Extracellular Vesicles Act as Nano-Transporters of Tyrosine Kinase Inhibitors to Revert Iodine Avidity in Thyroid Cancer

• Main Authors: Ramya Lakshmi Rajendran (Author), Sanjita Paudel (Author), Prakash Gangadaran (Author), Ji Min Oh (Author), Eun Jung Oh (Author), Chae Moon Hong (Author), Sangkyu Lee (Author), Ho Yun Chung (Author), Jaetae Lee (Author), Byeong-Cheol Ahn (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new approach for using extracellular vesicles (EVs) to deliver tyrosine kinase inhibitors (TKIs) to enhance iodine avidity in radioactive iodine-refractory thyroid cancer is needed. We isolated and characterized primary human adipose-derived stem cells (ADSCs) and isolated their EVs. The EVs were...