Hypermethylation of SOX2 Promoter in Endometrial Carcinogenesis

• Main Authors: Oscar Gee-Wan Wong (Author), Zhen Huo (Author), Michelle Kwan-Yee Siu (Author), HuiJuan Zhang (Author), LiLi Jiang (Author), Ester Shuk-Ying Wong (Author), Annie Nga-Yin Cheung (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2010-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

This paper aimed at investigating the expression and methylation profiles of SOX2, a gene coding for the stem cell-related transcription factor SOX2, in endometrial carcinomas. By methylation-specific polymerase chain reaction (MS-PCR), the methylation status of SOX2 promoter region in 72 endometria...