LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation

• Main Authors: Jian Sun (Author), Tongzhu Jin (Author), Zhihui Niu (Author), Jiayu Guo (Author), Yingying Guo (Author), Ruoxuan Yang (Author), Qianqian Wang (Author), Huiying Gao (Author), Yuhan Zhang (Author), Tianyu Li (Author), Wenxin He (Author), Zhixin Li (Author), Wenchao Ma (Author), Wei Su (Author), Liangliang Li (Author), Xingxing Fan (Author), Hongli Shan (Author), Haihai Liang (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with unknown etiology and limited therapeutic options. Activation of fibroblasts is a prominent feature of pulmonary fibrosis. Here we report that lncRNA DACH1 (dachshund homolog 1) is downregulated in the lungs of IPF patients and in an e...