Determination of a novel anticonvulsant drug GIZh-290 in rat plasma by liquid chromatography-tandem mass spectrometry

• Main Authors: P. O. Bochkov (Author), I. P. Khrustova (Author), A. A. Litvin (Author), G. B. Kolyvanov (Author), R. V. Shevchenko (Author), V. P. Zherdev (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

GIZh-290 is a new derivative of 4-phenylpyrrolidone, based on the structures of racetams that combine anticonvulsant and nootropic effects. The method of high-performance liquid chromatography with mass spectrometric detection was developed and validated for the quantitative determination of a new p...