Comparative Evaluation of Radiochemical and Biological Properties of <sup>131</sup>I- and [<sup>99m</sup>Tc]Tc(CO)<sub>3</sub>-Labeled RGD Analogues Planned to Interact with the α<sub>v</sub>β<sub>3</sub> Integrin Expressed in Glioblastoma

Comparative Evaluation of Radiochemical and Biological Properties of <sup>131</sup>I- and [<sup>99m</sup>Tc]Tc(CO)<sub>3</sub>-Labeled RGD Analogues Planned to Interact with the α<sub>v</sub>β<sub>3</sub> Integrin Expressed in Glioblastoma

Radiolabeled peptides with high specificity for overexpressed receptors in tumor cells hold great promise for diagnostic and therapeutic applications. In this work, we aimed at comparing the radiolabeling efficiency and biological properties of two different RGD analogs: GRGDYV and GRGDHV, labeled w...

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Main Authors: Danielle V. Sobral (Author), Leonardo L. Fuscaldi (Author), Ana Claudia R. Durante (Author), Fernanda F. Mendonça (Author), Larissa R. de Oliveira (Author), Ana Cláudia C. Miranda (Author), Jorge Mejia (Author), Wagner R. Montor (Author), Marycel F. de Barboza (Author), Luciana Malavolta (Author)
Format: Book
Published: MDPI AG, 2022-01-01T00:00:00Z.
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