Rapid Discovery of the Potential Toxic Compounds in Polygonum multiflorum by UHPLC/Q-Orbitrap-MS-Based Metabolomics and Correlation Analysis

• Main Authors: Lifeng Han (Author), Piao Wang (Author), Yulan Wang (Author), Qianyu Zhao (Author), Fang Zheng (Author), Zhiying Dou (Author), Wenzhi Yang (Author), Limin Hu (Author), Caixiang Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dry roots of Polygonum multiflorum (PM), involving both the raw and processed materials, are widely used as the traditional Chinese medicine for treating various diseases in China. Hepatotoxicity has been occasionally reported in patients who consume PM. Unfortunately, no definite criteria are c...