Ameliorative effects of omega-lycotoxin-Gsp2671e purified from the spider venom of Lycosa praegrandis on memory deficits of glutamate-induced excitotoxicity rat model

• Main Authors: Mohammad Keimasi (Author), Kowsar Salehifard (Author), Marzieh Shahidi (Author), Fariba Esmaeili (Author), Noushin Mirshah Jafar Esfahani (Author), Siamak Beheshti (Author), Mohammadreza Amirsadri (Author), Faezeh Naseri (Author), Mohammadjavad Keimasi (Author), Najmeh Ghorbani (Author), Mohammad Reza Mofid (Author), Majid Moradmand (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Memory impairment is one of the main complications of Alzheimer's disease (AD). This condition can be induced by hyper-stimulation of N-Methyl-D-aspartate receptors (NMDARs) of glutamate in the hippocampus, which ends up to pyramidal neurons determination. The release of neurotransmitters relie...