Safety and efficacy results of simulated post-exposure prophylaxis with human immune globulin (HRIG; KEDRAB) co-administered with active vaccine in healthy subjects: a comparative phase 2/3 trial

• Main Authors: Mark A. Matson (Author), Eran Schenker (Author), Michal Stein (Author), Vladislava Zamfirova (Author), Huy-Binh Nguyen (Author), Garrett E. Bergman (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We conducted a clinical trial to assess the safety and putative efficacy of an additional human rabies immune globulin (HRIG; KEDRAB) versus an older product (Comparator, HyperRAB S/D® [Grifols]) and determine whether HRIG interferes with development of endogenous antibodies versus Comparator, when...